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Postion:Product Catalog >NT-0249
NT-0249
  • NT-0249

NT-0249 NEW

Price $195 $483 $692
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-12

Product Details

Product Name: NT-0249 CAS No.: 2763617-39-4
Purity: 98.11% Supply Ability: 10g
Release date: 2026/05/12

Product Introduction

Bioactivity

NameNT-0249
DescriptionNT-0249 is an orally active inhibitor of the inflammatory vesicle NLRP3 with anti-inflammatory activity that reverses high-fat diet-induced obesity, systemic inflammation, and astrocyte hyperplasia.
In vivoTwo structurally distinct NLRP3 inhibitors, NT-0249 and NT-0796, were able to reverse obesity in a mouse model of diet-induced obesity (DIO), and DIO-driven hypothalamic glial fibrillary acidic protein (GFAP) expression could be blocked by administration of NT-0249 or NT-0796. [1]
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsNLRP3
Inhibitors RelatedStavudine | Ascorbyl palmitate | Citraconic acid | Trimethylamine N-oxide | Teneligliptin hydrobromide | Resveratrol | NLRP3-IN-2 | Aluminum Hydroxide | N4-Acetylcytidine | (S)-(+)-Carvone | MCC950 | Diisononyl phthalate
Related Compound LibrariesNF-κB Signaling Compound Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Anti-Ovarian Cancer Compound Library | Pyroptosis Compound Library | Drug Repurposing Compound Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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