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Postion:Product Catalog >NX-2127
NX-2127
  • NX-2127

NX-2127 NEW

Price $100 $247 $372
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: NX-2127 CAS No.: 2416131-46-7
Purity: 99.07% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameNX-2127
DescriptionNX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 cells.NX-2127 potently catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) at 25 nM and 54 nM, respectively. NX-2127 is associated with the immune system, stimulating T cell activation and increasing IL-2 production in primary human T cells.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information2% DMSO+40% PEG300+5% Tween 80+53% Saline : 3 mg/mL (4.17 mM), Suspension.
DMSO : 150 mg/mL (208.38 mM), Sonication is recommended.
KeywordsNX-2127 | BTK
Inhibitors Relatedevobrutinib | (±)-Zanubrutinib | Bavdegalutamide | Sunvozertinib | Ibrutinib | dBET6 | IBT6A | Orelabrutinib | ARV-825 | Remibrutinib | Lenalidomide | Vepdegestrant
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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