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Postion:Product Catalog >API>Circulatory system drugs>Anti Shock vasoactive drugs>Olanzapine
Olanzapine
  • Olanzapine

Olanzapine NEW

Price $30 $39 $55
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-04-21

Product Details

Product Name: Olanzapine CAS No.: 132539-06-1
Purity: 99.90% Supply Ability: 10g
Release date: 2026/04/21

Product Introduction

Bioactivity

NameOlanzapine
DescriptionOlanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
In vitroOlanzapine is a potent antagonist of DA and 5-HT receptors, which elevates the extracellular levels of DA metabolites, such as DOPAC, and the DA metabolite 3-methoxytyramine, in the prefrontal cortex, nucleus accumbens, and striatum of rats. Subcutaneous injections of Olanzapine (0.5-10 mg/kg) increase the levels of dopamine (DA) and norepinephrine (NE) in these regions in a dose-dependent manner. Additionally, Olanzapine significantly inhibits insulin, leading to the onset of obesity.
In vivoOlanzapine interacts with several key receptors associated with schizophrenia, demonstrating nanomolar affinity for dopamine, serotonin, alpha-1 adrenergic, and cholinergic receptors. Specifically, Olanzapine selectively targets striatal dopamine in the limbic and cortical regions of the brain, exhibiting no selectivity towards dopamine receptor subtypes.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 240 mg/mL (768.17 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (16 mM), Sonication is recommended.
KeywordsSH-SY5Y | Serotonin Receptor | Olanzapine | neuronal | Muscarinic acetylcholine receptor | Mitophagy | Mitochondrial Autophagy | mitochondrial | mAChR | LY-170053 | LY 170053 | Inhibitor | inhibit | HT | DopamineReceptor | Dopamine Receptor | Dopamine | damage | cell | Beta Receptor | Autophagy | Apoptosis | antipsychotic | anticholinergic | AdrenergicReceptor | Adrenergic Receptor | 5-hydroxytryptamine Receptor | 5HTReceptor | 5-HT2 | 5-HT Receptor | 5HT Receptor | 5-HT
Inhibitors RelatedStavudine | Aceglutamide | Hemin | Urea | Guanidine hydrochloride | Hydroxychloroquine | Metronidazole | Formamide | Paeonol | Naringin | N,N-Dicyclohexylcarbodiimide | Alginic acid
Related Compound LibrariesFailed Clinical Trials Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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