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Postion:Product Catalog >ONO 1301
ONO 1301
  • ONO 1301

ONO 1301 NEW

Price $595 $987 $1730
Package 25mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: ONO 1301 CAS No.: 176391-41-6
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

NameONO 1301
DescriptionONO 1301 is a prostaglandin I2 mimetic compound with inhibitory activity against thromboxane A2 synthase, and it suppresses pancreatic fibrosis in the DBTC-induced chronic pancreatitis model by inhibiting monocyte activity through both direct effects of ONO 1301 and induction of hepatocyte growth factor. ONO 1301 also promoting HGF synthesis and elevating intracellular cyclic AMP levels via IP-receptor signaling, highlighting its therapeutic relevance in fibrotic disease and inflammation research.
In vitroIn platelet function assays, ONO 1301 inhibited collagen-induced platelet aggregation in a concentration-dependent manner with an IC50 of 460 nM. Additionally, in primary osteoblasts and ST2 stromal cells, treatment with the compound (0-1000 nM) significantly increased alkaline phosphatase (ALP) activity, serving as a marker for osteoblast differentiation [1].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 40 mg/mL (93.35 mM), Sonication is recommended.
KeywordsOno 1301

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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