Product Details
| Product Name:
Org-12962 |
CAS No.:
132834-56-1 |
| Purity:
98.38% |
Supply Ability:
10g |
| Release date:
2026/07/06 |
Product Introduction
Bioactivity
| Name | Org-12962 |
| Description | Org-12962 is an effective and selective 5-HT2C?receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A?and 5-HT2B receptors (pEC50s: 6.38 and 6.28, respectively). |
| In vivo | Org-12962 is dissolved or microsuspended in 0.3% v/v Tween 80 in physiological saline (NaCl 0.9%). Org-12962 (intraperitoneal injection; 0.3-3.2 mg/kg) obviously enhances the postinjection frequency thresholds for self-interruption (F3.71=11.40) [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (18.82 mM), Sonication is recommended.
DMSO : 225 mg/mL (846.95 mM), Sonication is recommended.
|
| Keywords | Org-12962 | Org12962 | Org 12962 | 5HTReceptor | 5-HT2C Receptor | 5-HT2C | 5-HT2B Receptor | 5-HT2B | 5-HT2A Receptor | 5-HT2A | 5HT Receptor |
| Inhibitors Related | Alverine citrate | Sevoflurane | Dapoxetine hydrochloride | Cefaclor monohydrate | Clozapine N-Oxide | 1,8-Cineole | Dopamine hydrochloride | Cloperastine hydrochloride | Mianserin hydrochloride | Trazodone hydrochloride | Cinchonidine | Doxepin hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Antidepressant Compound Library | Anti-Alzheimer's Disease Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | CNS-Penetrant Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | GPCR Compound Library | Anti-Cancer Compound Library | Serotonin Receptor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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United States