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Postion:Product Catalog >ORY1001
ORY1001
  • ORY1001

ORY1001 NEW

Price $54 $76 $136
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: ORY1001 CAS No.: 1431326-61-2
Purity: 99.85% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameORY1001
DescriptionORY1001 (ORY 1001) is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor, with high selectivity against related FAD dependent aminoxidases with IC50 of <20 nM.
In vitroIn THP-1 (MLL-AF9) cells, ORY-1001 results in a time/dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. ORY-1001 also induces apoptosis in THP-1 and inhibits proliferation and colony formation of MV(4;11) (MLL-AF4) cells. [1]
In vivoIn rodent MV(4;11) xenografts, ORY-1001 (<0.020 mg/kg, p.o.) leads to significantly reduced tumor growth. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 7.81 mg/mL (25.75 mM), Sonication is recommended.
Ethanol : 1 mg/mL (3.3 mM), Sonication is recommended.
H2O : 56 mg/mL (184.65 mM), Sonication is recommended.
KeywordsRG6016 | RG 6016 | ORY-1001 (RG-6016) | ORY1001 | LSD1/KDM1A | HistoneDemethylase | Histone Demethylase
Inhibitors RelatedLSD1-IN-24 | Procaine | TFMB-(R)-2-HG | GSK-J4 | FY-21 | Phenelzine sulfate | Pulrodemstat HCl | Daminozide | Zavondemstat | AS8351 | Procaine hydrochloride | Eicosapentaenoic Acid
Related Compound LibrariesHighly Selective Inhibitor Library | Anti-Lung Cancer Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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