OSMI-3 NEW
| Price | $397 | $949 | $1290 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-10 |
Product Details
| Product Name: OSMI-3 | CAS No.: 2260791-13-5 |
| Purity: 99.35% | Supply Ability: 10g |
| Release date: 2026/06/10 |
Product Introduction
Bioactivity
| Name | OSMI-3 |
| Description | OSMI-3 is a potent and cell-permeable inhibitor of O-GlcNAc transferase (OGT) for the study of cancer and cardiovascular disease. |
| In vitro | Treatment with OSMI-3 (Compound 2b) at concentrations ranging from 20 to 50 μM for durations of 4 to 24 hours in HCT116 cells significantly decreases O-GlcNAc levels, demonstrating more sustained cellular effects compared to OSMI-2[1].In cells treated with OSMI-3 (Compound 2b), there is an observable decrease in HCF-1 cleavage products and an increase in uncleaved HCF-1. Given that OGT knockdown is known to reduce cell proliferation, the impact of OSMI-3 on cell growth over 96 hours is monitored. Although there is no evidence of apoptosis, a reduction in cell growth over time is evident, consistent with the results observed with OGT knockdown[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | OSMI-3 | OSMI3 | OSMI 3 | O-GlcNAc transferase (OGT) |
| Inhibitors Related | Alendronate sodium trihydrate | Serotonin hydrochloride | D(+)-Raffinose pentahydrate | 2,2'-Methylenebis(6-tert-butyl-4-methylphenol) | Risedronic Acid | Cyclandelate | Entacapone | CBHcy | 2-Furoic acid | Eliglustat hemitartrate | Flopropione | Tolcapone |
| Related Compound Libraries | Bioactive Compound Library | Post-Translational Modification Compound Library | Inhibitor Library | Lipid Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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