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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Neuronal Signaling>AChR inhibitor>Otilonium bromide
Otilonium bromide
  • Otilonium bromide

Otilonium bromide NEW

Price Get Latest Price
Package 1KG 25KG
Min. Order: 1KG
Supply Ability: 5000kg
Update Time: 2026-06-03
Related documents: COA

Product Details

Product Name: Otilonium bromide CAS No.: 26095-59-0
EC-No.: 247-457-4 Min. Order: 1KG
Purity: 99% Supply Ability: 5000kg
Release date: 2026/06/03

Otilonium bromide is primarily used as an antispasmodic medication for the treatment of gastrointestinal disorders, specifically those involving smooth muscle spasms and motility issues. Its main applications are:

  1. Irritable Bowel Syndrome (IBS):

    • This is its primary and most common application.

    • It effectively relieves the abdominal pain, cramping, bloating, and discomfort associated with IBS, particularly in subtypes where these symptoms predominate (like IBS-Mixed or IBS-Diarrhea predominant).

    • It helps normalize bowel function by reducing spasms.

  2. Other Functional Gastrointestinal Disorders (FGIDs):

    • It can be used to treat symptoms like abdominal pain and cramps arising from other functional disorders of the gut where spasms are a key feature.

  3. Symptomatic Treatment of Abdominal Pain/Spasm:

    • Doctors may prescribe it for abdominal pain and cramps caused by various conditions where smooth muscle spasm is implicated, even if not strictly IBS.

  4. Diverticular Disease:

    • It is sometimes used to manage pain and spasm associated with symptomatic uncomplicated diverticular disease of the colon.

How it Works (Mechanism of Action):

  • Calcium Channel Blocker: Primarily acts as an antagonist at L-type calcium channels on the smooth muscle cells of the gastrointestinal tract (especially the colon). By blocking calcium influx, it prevents muscle contraction and reduces spasms.

  • Antimuscarinic Effects: It also has some antagonistic activity at muscarinic receptors, which further contributes to its smooth muscle relaxant effects and may reduce secretions.

  • Local Action: It acts locally within the gut lumen and on the intestinal wall, with minimal systemic absorption. This contributes to its favorable safety profile.


Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

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