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Postion:Product Catalog >PACOCF3
PACOCF3
  • PACOCF3

PACOCF3 NEW

Price $55 $98 $168
Package 10mg 25mg 50mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: PACOCF3 CAS No.: 141022-99-3
Purity: 99.93% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NamePACOCF3
DescriptionPACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PACOCF3 alters Ca 2+ signaling in renal tubular cells [1] [2].
In vitroPACOCF3 does not affect basal cytosolic free calcium concentrations ([Ca2+]i) at 20 μM, but a dosage between 50-250 μM triggers an increase in [Ca2+]i through the stimulation of extracellular Ca2+ entry, which can be partially inhibited by 50 μM La3+[2]. This PACOCF3-induced effect is negated when extracellular Ca2+ is removed. At a concentration of 10 μM, PACOCF3 amplifies the peak and the area under the curve of the [Ca2+]i surge elicited by 10 μM ATP and 1 μM bradykinin, by enhancing extracellular Ca2+ influx without altering internal Ca2+ release[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 45 mg/mL (145.9 mM), Sonication is recommended.
Keywordsphospholipase A2 | Palmityltrifluoromethylketone | PACOCF-3 | PACOCF3 | PACOCF 3
Inhibitors RelatedNeomycin sulfate | Levamisole hydrochloride | 1-Naphthaleneacetic acid potassium salt | Difluprednate | trans-Benzylideneacetone | Benzylideneacetone | Omeprazole | Indomethacin | Darapladib | 1-Naphthaleneacetic acid | Lansoprazole | Magnesium sulfate
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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