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Postion:Product Catalog >PBD-150
PBD-150
  • PBD-150

PBD-150 NEW

Price $35 $56 $91
Package 2mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: PBD-150 CAS No.: 790663-33-1
Purity: 99.68% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NamePBD-150
DescriptionPBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)
In vivoA glutaminyl cyclase (QC) inhibitor, PBD150, was shown to be able to reduce the deposition of pyroglutamate-modified amyloid-β peptides in brain of transgenic mouse models of Alzheimer disease, leading to a significant improvement of learning and memory in those transgenic animals[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (12.48 mM), Sonication is recommended.
DMSO : 125 mg/mL (390.13 mM), Sonication is recommended.
Keywordsβ-amyloid peptide | βAmyloid | β Amyloid | PBD-150 | PBD150 | PBD 150 | Inhibitor | inhibit | glutaminyl cyclase (hQC) Y115E-Y117E | BetaAmyloid | Beta Amyloid | bAmyloid | b Amyloid | Amyloid-β | Alzheimer | Abeta
Inhibitors RelatedBenzenesulfonamide | Deferoxamine Mesylate | Cromolyn sodium | HEPPS | Phytic acid sodium salt | Rutin | 10-Undecenoic acid | Pyridoxal phosphate | 2,4-Di-tert-butylphenol | Chlorzoxazone | Methyl tridecanoate | Glimepiride
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Anti-Alzheimer's Disease Compound Library | Neuronal Signaling Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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