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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>PCO371
PCO371
  • PCO371

PCO371 NEW

Price $61 $147 $218
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-19

Product Details

Product Name: PCO371 CAS No.: 1613373-33-3
Purity: 98.03% Supply Ability: 10g
Release date: 2026/05/19

Product Introduction

Bioactivity

NamePCO371
DescriptionPCO371 belongs to small molecule agonists and is a full PTH1R (parathyroid hormone receptor 1) agonist with oral activity, cell permeability, and selectivity for PTH1R (no effect on PTH2R). This compound is used in research on PTH1R activation mechanisms and related signaling pathways.
In vitroMethods: The in vitro activity of PCO371 was validated using a cAMP accumulation assay in AD293 cells. Cells were incubated with various concentrations of PCO371 for 30 minutes. Results: PCO371 induced cAMP levels comparable to PTH, indicating that PCO371 is a full G protein agonist of PTH1R. Data were obtained from three independent experiments, each with three technical replicates, and normalized to the maximum response of PTH.[1]
StorageKeep away from direct sunlight,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 120 mg/mL (188.78 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (7.87 mM), Sonication is recommended.
KeywordsThyroidhormonereceptor(THR) | Thyroidhormonereceptor | thyroid hormone receptor-1 (PTHR1) | Thyroid hormone receptor(THR) | Thyroid hormone receptor | THR | PTHR1 | PCO-371 | PCO371 | PCO 371 | Inhibitor | inhibit
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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