PF-06305591 NEW
| Price | $44 | $97 | $178 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-17 |
Product Details
| Product Name: PF-06305591 | CAS No.: 1449473-97-5 |
| Purity: 99.88% | Supply Ability: 10g |
| Release date: 2026/07/17 |
Product Introduction
Bioactivity
| Name | PF-06305591 |
| Description | PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM). |
| In vitro | PF-06305591 shows high NaV selectivity, passive permeability, hERG activity, and in vitro metabolic stability[1]. |
| In vivo | PF-06305591 shows good bioavailability in rats and can be used in studies about the treatment of pain[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 10 mg/mL (36.45 mM), Suspension. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (7.29 mM), Sonication is recommended. DMSO : 240 mg/mL (874.76 mM), Sonication is recommended. |
| Keywords | SodiumChannel | Sodium Channel | PF6305591 | PF-06305591 | PF06305591 | PF 6305591 | PF 06305591 | NaV1.8 |
| Inhibitors Related | Phenytoin sodium | Procaine | Ranolazine dihydrochloride | Tetracaine hydrochloride | Lidocaine | Safinamide | Permethrin | Valproic Acid | L-Aspartic aicd sodium | Lidocaine hydrochloride | Mebeverine hydrochloride | Dibucaine |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Sodium Channel Targeted Library | Drug Repurposing Compound Library | Inhibitor Library | Neuroprotective Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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