PF 1022A NEW
| Price | $68 | $163 |
| Package | 1mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-15 |
Product Details
| Product Name: PF 1022A | CAS No.: 133413-70-4 |
| Purity: 98.93% | Supply Ability: 10g |
| Release date: 2026/05/15 |
Product Introduction
Bioactivity
| Name | PF 1022A |
| Description | PF 1022A is a cyclooctadepsipeptide natural product produced by fungal fermentation with anthelmintic activity. As an ionophore-like compound, PF 1022A forms complexes with metal ions and disrupts ion homeostasis and membrane potential in parasites, leading to its anthelmintic effects. It shows significant activity against the poultry nematode Ascaridia galli. |
| In vitro | PF1022A is a novel anthelmintic that binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes. PF1022A binds to GABA receptors, which might contribute to the anthelmintic effect. Like other cyclodepsipeptides, PF1022A acts as an ionosphere. PF 1022A showed strong anthelmintic activities against Ascaridia galli in chickens. PF1022A showed low activity on embryonation but significantly inhibited egg hatch (10 and 100 μg/ml), whereas albendazole (10 and 100 μg/ml) revealed statistically significant inhibitions of both embryonation and egg hatch. PF1022A (1-100 μg/ml) fullly inhibited larval movement at most examination points [1][2][3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (84.28 mM), Sonication is recommended. 10% DMSO+90% Corn Oil : 2 mg/mL (2.11 mM), Sonication is recommended. |
| Keywords | PF 1022A |
| Inhibitors Related | Flubendazole | Kojic acid | Gum arabic | Urethane | Hydroxychloroquine | Metronidazole | 2-Amino-2-methyl-1-propanol | Doxycycline | Fenpyroximate | Methylene Blue trihydrate | Coumaran | Benzimidazole |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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