PF-4800567 NEW
| Price | $38 | $58 | $137 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: PF-4800567 | CAS No.: 1188296-52-7 |
| Purity: 99.74% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | PF-4800567 |
| Description | PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ. |
| In vitro | PF-4800567 shows inhibitory activity against CK1ε and CK1δ in whole cells, with IC50s of 2.65 and 20.38 μM, respectively. PF-4800567 (0.01-10 μM) blocks CK1?-mediated PER3 nuclear localization mediated by CK1? and suppresses PER2 degradation at 1 μM. In addition, PF-4800567 (32 nM) has little effect on the circadian clock [1]. |
| In vivo | PF-4800567 (100 mg/kg, s.c.) is quickly absorbed and distributed in the plasma and brain of mice [1]. |
| Storage | Keep away from direct sunlight,Store under nitrogen,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 62.5 mg/mL (173.7 mM), Sonication is recommended. 10% DMSO+90% Saline : < 6.25 mg/mL (17.37 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 6.25 mg/mL (17.37 mM), Solution. |
| Keywords | PF-4800567 | PF4800567 | PF 4800567 | Inhibitor | inhibit | CK1ε | CaseinKinase | Casein Kinase |
| Inhibitors Related | Hematein | TBCA | Ellagic acid | Casein | Casein Kinase II Inhibitor IV | Emodin | AS-252424 | LY-364947 | TA-01 | CK2/ERK8-IN-1 | Casein kinase 1δ-IN-14 | LY294002 |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Multi-Target Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Metabolism Disease Compound Library | Wnt/Hedgehog/Notch Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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