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Postion:Product Catalog >PFE-360
PFE-360
  • PFE-360

PFE-360 NEW

Price $68 $172 $239
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: PFE-360 CAS No.: 1527475-61-1
Purity: 99.91% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NamePFE-360
DescriptionPFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase, with an in vivo IC50 of 2.3 nM.
In vivoPFE-360 (4 mg/kg and 7.5 mg/kg, orally, BID, 10-12 weeks) treatment effectively reduces the LRRK2-pSer935/total LRRK2 ratio. It has no significant adverse effects[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 3.09 mg/mL (10.02 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (3.24 mM), Sonication is recommended.
KeywordsPFE-360 | PFE360 | PFE 360 | PF06685360 | PF 06685360 | LRRK2 | Leucine-rich repeat kinase 2 | Inhibitor | inhibit
Inhibitors RelatedIKK 16 | URMC-099 | GNE0877 | CZC-25146 | GSK2578215A | GNE-9605 | Indazole | CZC-54252 hydrochloride | GNE-7915 | LRRK2 inhibitor 1 | LRRK2-IN-7 | BIX 02565
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Kinase Inhibitor Library | Anti-Parkinson's Disease Compound Library | Autophagy Compound Library | Post-Translational Modification Compound Library | Inhibitor Library | NO PAINS Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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