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Postion:Product Catalog >PFM03
PFM03
  • PFM03

PFM03 NEW

Price $1080 $1430
Package 25mg 50mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: PFM03 CAS No.: 1558598-48-3
Purity: 99.81% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NamePFM03
DescriptionPFM03 is an endonuclease inhibitor that specifically blocks Mre11 and is also able to reduce MRN endonuclease activity by 98%, blocking hMRN-mediated endonucleotomy and nuclear exocytosis processes on the protein-binding end of the 5 ' and 3 ' chains.
In vitroTreatment with 50–400 μM PFM03 for 30 minutes specifically inhibits the endonuclease activity of MRE11 [1]. Treatment with 100 μM PFM03 for 30 minutes does not impair double-strand break (DSB) repair in G2-phase (CENPF?) cells [1]. Treatment with 50 μM PFM03 for 8 hours increases non-homologous end joining (NHEJ) activity while suppressing homologous recombination (HR) in cells [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (11.25 mM), Sonication is recommended.
DMSO : 80 mg/mL (272.67 mM), Sonication is recommended.
Inhibitors RelatedPFM39 | T4 endonuclease VII | Endonuclease IV | Deoxyribonuclease II | PFM01 | O-Glycoprotease | dsDNase | MU147 | MUS81-IN-1 | PNR-3-80 | FEN1-IN-SC13 | T5 Exonuclease
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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