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Postion:Product Catalog >PHA 543613
PHA 543613
  • PHA 543613

PHA 543613 NEW

Price $46 $109 $178
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-25

Product Details

Product Name: PHA 543613 CAS No.: 478149-53-0
Purity: 99.96% Supply Ability: 10g
Release date: 2026/05/25

Product Introduction

Bioactivity

NamePHA 543613
DescriptionPHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.
In vivoIn rats, PHA-543613 (0.3 mg/kg) reverses Scopolamine-induced short-term memory deficits[2]. Intraperitoneal injection of PHA-543613 (4 and 12 mg/kg) increases p-Akt and decreases p-GSK-3 and CC3 expressions in the ipsilateral hemisphere. PHA-543613 reduces neuronal cell death in the perihematomal area[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 225 mg/mL (829.31 mM), Sonication is recommended.
H2O : < 30.78 mg/mL, Sonication is recommended.
Keywordsα7 nAChR | PHA-543613 | PHA543613 | PHA 543613 hydrochloride | PHA 543613
Inhibitors RelatedAdiphenine hydrochloride | Levamisole hydrochloride | Ethyl (triphenylphosphoranylidene) acetate | Urethane | Hexamethonium Bromide | Ribavirin | Adenine | Mitotane | Choline chloride | Propoxur | N,N-Dicyclohexylcarbodiimide | Arecoline
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Anti-Alzheimer's Disease Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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