PKI-402 NEW
| Price | $44 | $71 | $143 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: PKI-402 | CAS No.: 1173204-81-3 |
| Purity: 99.94% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | PKI-402 |
| Description | PKI-402 is a potent PI3K and mTOR inhibitor. PKI-402 inhibits PI3Kα, mTOR, PI3Kβ, PI3Kδ and PI3Kγ with IC50s of 2, 3, 7, 14 and 16 nM, respectively. |
| In vitro | PKI-402 causes in vitro growth inhibition of human tumor cell lines derived from a diverse set of human tumor tissues, including breast, brain (glioma), pancreas, and non-small cell lung cancer (NSCLC) tissues[1]. |
| In vivo | PKI-402 exhibits antitumor efficacy via intravenous administration in breast [MDA-MB-361: Her2+ and PIK3CA (E545K)], glioma (U87MG and PTEN), and NSCLC (A549; K-Ras and STK11) xenograft models, with induced regression observed specifically in the MDA-MB-361 model. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 0.47 mg/mL (0.82 mM), Suspension. DMSO : 4.68 mg/mL (8.2 mM), Sonication is recommended. |
| Keywords | PKI-402 | PKI402 | PKI 402 |
| Inhibitors Related | Musk ketone | Stearamide | L-Leucine | Myricetin | Creatine monohydrate | Hyaluronic acid | L-Proline | Isoprenaline hydrochloride | Metformin | Methyl eugenol | Quercetin | Dihydromyricetin |
| Related Compound Libraries | Glycolysis Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $997.00 |
VIP2Y
|
TargetMol Chemicals Inc.
|
2026-04-20 | |
| $2730.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-05-27 | |
|
VIP1Y
|
Wuhan Hugarise New Material Co.,Ltd
|
2026-05-12 | ||
| $2.00 |
VIP8Y
|
Career Henan Chemical Co
|
2019-07-06 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY