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Postion:Product Catalog >Plx-4032
Plx-4032
  • Plx-4032

Plx-4032 NEW

Price $50 $72 $100
Package 10mg 50mg 100mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: Plx-4032 CAS No.: 1029872-54-5
Purity: 99.94% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NamePlx-4032
DescriptionPlx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
In vivoPLX-4032 and its related analogs are highly potent inhibitors of B-Raf activity, with 3-fold selectivity for the V600E mutation over the wild-type kinase.?In preclinical models, PLX-4032 and its analogs inhibited the growth of BRAFV600E-positive melanoma cell lines both in vitro and in vivo[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 7.29 mg/mL (14.88 mM), Solution.
Ethanol : 1.41 mg/mL (2.88 mM), Sonication is recommended.
DMSO : 72.86 mg/mL (148.72 mM), Sonication is recommended.
10% DMSO+90% Saline : < 7.29 mg/mL (14.88 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
KeywordsPlx-4032 | Plx4032 | Plx 4032 | B-Raf | 18504-65-1
Inhibitors RelatedRegorafenib monohydrate | Exarafenib | Doramapimod | Vemurafenib | Sulindac sulfide | Sorafenib | Regorafenib | Dabrafenib | Dabrafenib Mesylate | LY3009120 | GW 441756 | RMC-7977
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Post-Translational Modification Compound Library | Inhibitor Library | FDA-Approved Kinase Inhibitor Library | Covalent Inhibitor Library | NMPA-Approved Drug Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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