Product Details
| Product Name:
Polygodial |
CAS No.:
6754-20-7 |
| Purity:
99.84% |
Supply Ability:
10g |
| Release date:
2026/07/15 |
Product Introduction
Bioactivity
| Name | Polygodial |
| Description | Polygodial (Tadeonal) is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana. |
| In vitro | When tested on S. cerevisiae, polygodial proved to be fungicidal rather than fungistatic. When the cells of S. cerevisiae are treated in vitro with polygodial for 10 min, the cell membrane becomes severely damaged, and many vesicles, possibly formed from the fragmented cell membrane, can be observed within the cytoplasm[1]. |
| In vivo | Polygodial (0.1 to 10 mg kg(-1), i.p.) produced significant inhibition of acetic acid, kaolin and zymosan-induced writhing in mice, being about 14 to 27-fold more potent than the hydroalcoholic extract at the ID50 level[2]. |
| Storage | Keep away from direct sunlight,
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 65 mg/mL (277.39 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (8.53 mM), Sonication is recommended.
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| Keywords | Polygodial | Poligodial | Inhibitor | inhibit | Fungal | Antifungal,Potentiator,sesquiterpene,anti-hyperalgesic | Antifungal |
| Inhibitors Related | Calcium Propionate | Dehydroacetic acid sodium | Potassium gluconate | D-Gluconic acid (solution) (50% in H2O) | Sulfacetamide sodium | Terbinafine hydrochloride | Benzyl propionate | Sodium formate | Geraniol | Magnesium acetate tetrahydrate | L-Citronellol | Benzimidazole |
| Related Compound Libraries | Terpene Natural Product Library | Bioactive Compound Library | Rare Natural Product Library | Anti-Fungal Compound Library | Antibiotics Library | Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Covalent Natural Product Library | Bioactive Compounds Library Max | Anti-Infection Compound Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Price |
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Suppliers |
Update time |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States