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Postion:Product Catalog >Biochemical Engineering>Natural Products>Polyphyllin I
Polyphyllin I
  • Polyphyllin I

Polyphyllin I NEW

Price $52 $89 $153
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-06-01

Product Details

Product Name: Polyphyllin I CAS No.: 50773-41-6
Purity: 99.50% Supply Ability: 10g
Release date: 2026/06/01

Product Introduction

Bioactivity

NamePolyphyllin I
DescriptionPolyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 250 mg/mL (292.39 mM), Sonication is recommended.
10% DMSO+90% Saline : < 10 mg/mL (11.7 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+40% PEG300+5% Tween-80+45% Saline : 1 mg/mL (1.17 mM), Sonication is recommended.
10% DMSO+90% Corn oil : 10 mg/mL (11.7 mM), Solution.
10% DMSO+90% (20% SBE-β-CD in Saline) : < 10 mg/mL (11.7 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : < 10 mg/mL (11.7 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
KeywordsProtein kinase B | Polyphyllin I | PKB | PDK-1 | PDK1 | mTOR | Mammalian target of Rapamycin | JNK | Inhibitor | inhibit | Autophagy | Apoptosis | Akt
Inhibitors RelatedStavudine | Aceglutamide | Hemin | Urea | Guanidine hydrochloride | Hydroxychloroquine | Metronidazole | Ethyl linoleate | Formamide | Paeonol | Naringin | Alginic acid
Related Compound LibrariesAnti-Tumor Natural Product Library | Traditional Chinese Medicine Monomer Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Selected Plant-Sourced Compound Library | Kinase Inhibitor Library | Saccharide and Glycoside Natural Product Library | Miao medicine Compound Library | Inhibitor Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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