Product Details
| Product Name:
PR5-LL-CM01 |
CAS No.:
1005307-86-7 |
| Supply Ability:
10g |
Release date:
2026/04/20 |
Product Introduction
Bioactivity
| Name | PR5-LL-CM01 |
| Description | PR5-LL-CM01 is an effective epigenetic modulator and histone deacetylase (HDAC) inhibitor. It alters chromatin structure and activates tumor suppressor gene transcription by increasing histone acetylation, showing significant anti-proliferative activity in solid tumor models. |
| In vitro | PR5-LL-CM01 potently inhibits PDAC and CRC cell growth by targeting PRMT5 to block NF-kB activation [1]. |
| In vivo | In NSG xenograft models, PR5-LL-CM01 (20 mg/kg i.p.) significantly inhibits PANC1 and HT29 tumor growth [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 8 mg/mL (19.92 mM), , when pH is adjusted to 3 with HCl.
|
| Keywords | PR5-LL-CM01 | PR-5-LL-CM01 | PR5LLCM01 | PR5 LL CM01 |
| Inhibitors Related | Panobinostat | Theophylline monohydrate | Valproic acid sodium salt | Methoxyacetic acid | Sodium 4-phenylbutyrate | Acefylline | Manganese chloride (tetrahydrate) | Curcumin | Valproic Acid | Sodium butanoate | 4-Phenylbutyric acid | Theophylline |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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