Product Details
| Product Name:
Procyclidine |
CAS No.:
77-37-2 |
| Supply Ability:
10g |
Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | Procyclidine |
| Description | Procyclidine (Tricyclamol; (±)-Procyclidine) is an anticholinergic agent that functions as a muscarinic receptor antagonist and an N-methyl-D-aspartate (NMDA) antagonist. It is used in studies of Parkinson's disease and related psychiatric disorders, including Soman-induced epilepsy [1][2]. |
| In vivo | Procyclidine, when administered subcutaneously at dosages between 0.3-6.0 mg/kg in conjunction with physostigmine (PhS), exhibits increased dose-dependent protective effects against soman in rats and guinea pigs, significantly reducing or entirely preventing seizures. The study utilized male Sprague-Dawley rats and Dunkin-Hartley male guinea pigs, observing a substantial enhancement in protection. Specifically, protection levels in rats enhanced by 1.92, 2.24, 3.95, and 5.07 times, and in guinea pigs by 3.00, 3.25, 4.50, and 4.70 times at dosages of 0.3, 1.0, 3.0, and 6.0 mg/kg, respectively. This combination treatment safeguarded neurological brain integrity, effectively preventing severe damage in critical brain areas such as the hippocampus, cortex, amygdala, and thalamus induced by soman exposure. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Adiphenine hydrochloride | Indole-2-carboxylic acid | Urethane | Decanoic Acid | N-Methylsarcosine | Hexamethonium Bromide | L-Glutamic acid | Adenine | Mitotane | N,N-Dicyclohexylcarbodiimide | Arecoline | Memantine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1.10
|
VIP6Y
|
Dideu Industries Group Limited
|
2025-11-18 |
United States