Propantheline NEW
| Price | $2140 | $2785 | $3520 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-20 |
Product Details
| Product Name: Propantheline | CAS No.: 298-50-0 |
| Supply Ability: 10g | Release date: 2026/04/20 |
Product Introduction
Bioactivity
| Name | Propantheline |
| Description | Propantheline is an orally active antagonist of muscarinic acetylcholine receptors (mAChRs), commonly employed to investigate smooth muscle dysfunction, hyperhidrosis, smooth muscle spasms or cramps in the stomach, intestines, or bladder, as well as involuntary urination [1] [2] [3]. |
| In vitro | Propantheline at concentrations ranging from 10 μM to 1 mM reduces the responsiveness of urinary bladder smooth muscle to Acetylcholine [1]. |
| In vivo | Propantheline, administered orally at doses ranging from 10-300 mg/kg, effectively reduced both fecal pellet count and the incidence of diarrhea in rats suffering from restraint stress-induced bowel dysfunction [3]. The compound demonstrated a dose-dependent efficacy, achieving an ED50 value of 41 mg/kg for decreasing fecal pellet count and an ED50 value of 64 mg/kg for reducing diarrhea incidence. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Adiphenine hydrochloride | Levamisole hydrochloride | Ethyl (triphenylphosphoranylidene) acetate | Urethane | Hexamethonium Bromide | Ribavirin | Adenine | Mitotane | Choline chloride | Propoxur | N,N-Dicyclohexylcarbodiimide | Arecoline |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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