Prostratin NEW
| Price | $211 |
| Package | 1mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Prostratin | CAS No.: 60857-08-1 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Prostratin |
| Description | Prostratin (12-Deoxyphorbol-13-acetate) is an orally active protein kinase C (PKC) activator with a Ki value of 12.5 nM.As an NF-κB activator, Prostratin activates HIV gene expression in T cells.Prostratin inhibits the growth of acute myeloid leukemia (AML) cell lines and enhances cytarabine-induced AML cell differentiation. In addition, Prostratin induced KRAS phosphorylation and inhibited the growth of KRAS-mutated tumors. |
| In vitro | Methods: Prostratin (125, 250, 500, 1000 nM) was used to treat HL-60, NB4, and U937 cells to evaluate its effect on leukemia cell growth. Results: Prostratin showed similar concentration- and time-dependent growth inhibition on all three cell lines. [2] |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 40 mg/mL (102.44 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble) 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 1.5 mg/mL (3.84 mM), Sonication is recommended. |
| Keywords | Prostratin |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Kojic acid | RMC-9805 | Lamivudine | 1,4-Naphthoquinone | Ethyl linoleate | D-Psicose | N,N-Dimethylacetamide | Daraxonrasib | Dextran sulfate sodium salt (MW 5000) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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