PRX-07034 hydrochloride NEW
| Price | $38 | $71 | $118 |
| Package | 10mg | 25mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-13 |
Product Details
| Product Name: PRX-07034 hydrochloride | CAS No.: 903580-39-2 |
| Purity: 99.17% | Supply Ability: 10g |
| Release date: 2026/06/13 |
Product Introduction
Bioactivity
| Name | PRX-07034 hydrochloride |
| Description | PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist (≥100-fold selectivity for the 5-HT(6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors. |
| In vitro | PRX-07034 is a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist with 100-fold selectivity over 68 other GPCRs, ion channels, and transporters, except for D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors. It demonstrated antagonist activity in cyclic AMP quantification (IC(50) = 19 nM) without affecting basal levels and showed no agonist activity up to 10 μM. At doses of 1 and 3 mg/kg, PRX-07034 significantly enhanced delayed spontaneous alternation and switching between place and response strategies, but did not affect initial learning of place or response discrimination. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.04 mM), Sonication is recommended. DMSO : 10 mg/mL (20.39 mM), Sonication is recommended. |
| Keywords | working | PRX-07034 Hydrochloride | PRX-07034 | PRX07034 | PRX 07034 | memory | flexibility | cognitive | 5HTReceptor | 5-HT6 | 5-HT Receptor | 5HT Receptor |
| Inhibitors Related | Alverine citrate | Sevoflurane | Dapoxetine hydrochloride | Cefaclor monohydrate | Clozapine N-Oxide | 1,8-Cineole | Dopamine hydrochloride | Cloperastine hydrochloride | Mianserin hydrochloride | Trazodone hydrochloride | Cinchonidine | Doxepin hydrochloride |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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