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Postion:Product Catalog >Pyoluteorin
Pyoluteorin
  • Pyoluteorin

Pyoluteorin NEW

Price $197 $497 $693
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: Pyoluteorin CAS No.: 25683-07-2
Purity: 99.93% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NamePyoluteorin
DescriptionPyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses related plant diseases. Additionally, Pyoluteorin induces apoptosis in human triple-negative breast cancer (MDA-MB-231) cells in vitro.
In vitroPyoluteorin, an antifungal compound composed of a bichlorinated pyrrole linked to a resorcinol moiety, was identified within a 24-kb genomic region of Pseudomonas fluorescens Pf-5[1]. It exhibits significant cytotoxicity towards MCF-7 cells (IC50=1.84 μM) and selective cytotoxicity against BT474, HCC1954, MAD-MB-468, MDA-MB-231, and MCF-10A cells with IC50 values of 9.75±0.16, 0.94±0.01, 3.89±0.08, 0.97±0.01, and 57.01±0.76 μM, respectively[2]. Treatment with Pyoluteorin (0.1-10 μM; for 24 hours) induces changes in apoptosis-related protein expressions and promotes cell apoptosis in MDA-MB-231 cells via Bcl-2 family proteins and caspase cascade, additionally causing cell cycle arrest in these human triple-negative breast cancer cells[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+90% Saline : 10 mg/mL (36.75 mM), Solution.
DMSO : 125 mg/mL (459.42 mM), Sonication is recommended.
KeywordsPyoluteorin | Antibiotic
Inhibitors RelatedNeomycin sulfate | Calcium Propionate | Stavudine | Aceglutamide | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Benzyl propionate | Metronidazole | Doxycycline | Formamide | Alginic acid
Related Compound LibrariesAnti-Tumor Natural Product Library | Apoptosis Compound Library | Polyphenolic Natural Product Library | Bioactive Compound Library | Anti-Fungal Compound Library | Antibiotics Library | Microbial Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Anhui Ruihan Technology Co., Ltd
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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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