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Postion:Product Catalog >API>Respiratory Drugs>Antitussives>Quercetin
Quercetin
  • Quercetin

Quercetin NEW

Price $42
Package 500mg
Supply Ability: 10g
Update Time: 2026-06-01

Product Details

Product Name: Quercetin CAS No.: 117-39-5
Purity: 97.14% Supply Ability: 10g
Release date: 2026/06/01

Product Introduction

Bioactivity

NameQuercetin
DescriptionQuercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90.
In vitroIn xenografts of human prostate cancer LNCaP and PC-3 cells, the combined administration of Quercetin (75 mg/kg) and 2-methoxyestradiol effectively inhibits tumor growth.
In vivoQuercetin inhibits TNF-induced LDH release, reduces EC-dependent adhesion of neutrophils to bovine pulmonary artery endothelial cells (BPAEC), and also suppresses DNA synthesis and cell proliferation in these cells. As a PI3K inhibitor (IC50=2.4 - 5.4 μM), quercetin strongly inhibits PI3K and Src kinases, moderately inhibits Akt1/2, and has a slight effect on PKC, p38, and ERK1/2.
StorageKeep away from moisture,Store under nitrogen,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5.7 mg/mL (18.86 mM), Solution.
H2O : < 1 mg/mL (insoluble or slightly soluble)
Ethanol : 4 mg/mL (13.23 mM), Sonication is recommended.
10% DMSO + 50% peg 300 + 5% Tween +35% Saline : 10 mg/mL (33.09 mM), Solution.
DMSO : 230 mg/mL (760.98 mM), Sonication is recommended.
KeywordsReactiveOxygenSpecies | Reactive Oxygen Species | Quercetin | PI3Kδ | PI3Kγ | PI3K | Phosphoinositide 3-kinase | Mitophagy | Mitochondrial Autophagy | Inhibitor | inhibit | Autophagy | Apoptosis
Inhibitors RelatedEthoxyquin | Stavudine | Aceglutamide | Allopurinol | Hemin | Guanidine hydrochloride | Hydroxychloroquine | Ethyl linoleate | Paeonol | Formamide | Naringin | Alginic acid
Related Compound LibrariesAnti-Tumor Natural Product Library | Polyphenolic Natural Product Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Flavor Natural Product library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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