RA190 NEW
| Price | $52 | $52 | $117 | $117 | $171 | $171 |
| Package | 1mg | 1mg | 5mg | 5mg | 10mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: RA190 | CAS No.: 1617495-03-0 |
| Purity: 97.70% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | RA190 |
| Description | RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13. |
| In vitro | Multiple myeloma (MM) lines, even those resistant to bortezomib, are sensitive to RA190 via endoplasmic reticulum stress-related apoptosis. RA190 stabilizes targets of human papillomavirus (HPV) E6 oncoprotein, and preferentially kills HPV-transformed cells. |
| In vivo | RA190 administration profoundly reduces growth of multiple myeloma and ovarian cancer xenografts, and oral RA190 treatment retards HPV16+ syngeneic mouse tumor growth, without impacting spontaneous HPV-specific CD8+ T cell responses. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Corn oil : < 10 mg/mL (16.76 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 235 mg/mL (393.79 mM), Sonication is recommended. 10% DMSO+90% (20% SBE-β-CD in Saline) : < 10 mg/mL (16.76 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+90% Saline : < 10 mg/mL (16.76 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : < 10 mg/mL (16.76 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| Keywords | RA-190 | RA190 | RA 190 | Proteasome | Inhibitor | inhibit | HeLa cell |
| Inhibitors Related | Tripterin | Sitagliptin | Teneligliptin hydrobromide | Sitagliptin phosphate monohydrate | 10-Undecenoic acid | Anagliptin | Aprotinin | 10-Undecenoic acid zinc salt | Vildagliptin | Sitagliptin phosphate | Alloxan monohydrate | 4'-Hydroxychalcone |
| Related Compound Libraries | Bioactive Compound Library | Ubiquitination Compound Library | Endoplasmic Reticulum Stress Compound Library | HIF-1 Signaling Pathway Compound Library | Protease Inhibitor Library | Hematonosis Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $52.00 |
VIP4Y
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TargetMol Chemicals Inc.
|
2026-06-02 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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