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Postion:Product Catalog >Raphin1 acetate
Raphin1 acetate
  • Raphin1 acetate

Raphin1 acetate NEW

Price $41 $65 $118
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Raphin1 acetate CAS No.: 2242616-04-0
Purity: 99.95% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameRaphin1 acetate
DescriptionRaphin1 acetate is a selective and orally bioavailable regulatory phosphatase PPP1R15B (R15B) inhibitor.
In vitroRaphin1, a selective inhibitor of R15B.?In cells, Raphin1 caused a rapid and transient accumulation of its phosphorylated substrate, resulting in a transient attenuation of protein synthesis.?In vitro, Raphin1 inhibits the recombinant R15B-PP1c holoenzyme, but not the closely related R15A-PP1c, by interfering with substrate recruitment.
In vivoRaphin1 was orally bioavailable, crossed the blood-brain barrier, and demonstrated efficacy in a mouse model of Huntington's disease.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 40 mg/mL (137.4 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (6.87 mM), Sonication is recommended.
KeywordsRaphin-1 acetate | Raphin1 acetate | Raphin-1 | Raphin1 | Raphin 1 | phosphatase?PPP1R15B (R15B) | Phosphatase | Inhibitor | inhibit
Inhibitors Relatedβ-Glycerophosphate disodium salt pentahydrate | Hexane-1,6-diol | 2-[dodecyl(2-hydroxyethyl)amino]ethanol | Idoxuridine | Cyclosporine | Tartaric acid disodium dihydrate | Stearic acid | CaMKP Inhibitor | L-Ascorbic acid 2-phosphate magnesium | Cyclosporin A | L-Ascorbic acid 2-phosphate | β-Glycerophosphate disodium salt hydrate
Related Compound LibrariesGlycometabolism Compound Library | Bioactive Compound Library | CNS-Penetrant Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Phosphatase Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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