一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
WhatsApp
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Retaspimycin Hydrochloride
Retaspimycin Hydrochloride
  • Retaspimycin Hydrochloride

Retaspimycin Hydrochloride NEW

Price $107 $177 $747
Package 2mg 5mg 50mg
Supply Ability: 10g
Update Time: 2026-07-16

Product Details

Product Name: Retaspimycin Hydrochloride CAS No.: 857402-63-2
Supply Ability: 10g Release date: 2026/07/16

Product Introduction

Bioactivity

NameRetaspimycin Hydrochloride
DescriptionRetaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).
In vitroRetaspimycin is an inhibitor of Hsp90. Retaspimycin can abrogate both the unfolded protein response element (UPRE) and ERSE-driven luciferase activity in non-treated U266 and MM.1s cells as well as in Tunicamycin (Tm)-treated cells. Incubation of Retaspimycin potently suppresses both Akt and MAPKs phosphorylation in both sensitive and Trastuzumab-resistant cells. Total levels of Akt decreased in all 4 cell lines (BT474, SKBR-3, HCC1569, and HCC1569) in a dose-dependent manner. However, levels of total MAPKs are not significantly altered with Retaspimycin treatment[2].
In vivoTumor regression of Trastuzumab-sensitive BT474 cell-derived xenografts independently induceed by Retaspimycin and Trastuzumab. Xenografts derived from BT474R cells continue to grow in the presence of Trastuzumab but are still sensitive to Retaspimycin. When used in combination, Retaspimycin and Trastuzumab add only marginal benefits to Retaspimycin monotherapy. Retaspimycin as a single agent is more efficacious than Trastuzumab in inhibiting tumor growth in HCC1569 xenografts[2].
StorageKeep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 56 mg/mL (89.72 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween-80+45% Saline : 3.3 mg/mL (5.29 mM), Sonication is recommended.
KeywordsRetaspimycin Hydrochloride | IPI504 | IPI 504 | HSP90 | GRP94
Inhibitors RelatedEthoxyquin | Adezmapimod | Tamoxifen | Palmitic acid sodium | Mequinol | 7-Aminocephalosporanic acid | Benzbromarone | Elesclomol | Rifabutin | Palmitic acid | Tamoxifen Citrate | Isoxazole

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$107.00
VIP4Y
TargetMol Chemicals Inc.
2026-07-15
$15.00
Zhuozhou Wenxi import and Export Co., Ltd
2021-07-13
$1.00
VIP7Y
Career Henan Chemical Co
2020-01-13
$15.00
Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09

TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY
武山县| 荃湾区| 黑山县| 洪洞县| 许昌市| 雅安市| 青川县| 阳东县| 枣庄市| 广南县| 大同县| 肇源县| 上饶县| 舒兰市| 沙河市| 聂荣县| 岳池县| 泽库县| 安远县| 郁南县| 翼城县| 汝南县| 永兴县| 木兰县| 兰考县| 石门县| 兴宁市| 商丘市| 澄江县| 乐陵市| 大悟县| 安西县| 淮滨县| 饶河县| 铁力市| 昌吉市| 洪湖市| 吴川市| 新疆| 吉木乃县| 合山市|