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Postion:Product Catalog >RIG012
RIG012
  • RIG012

RIG012 NEW

Price $67 $160 $240
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: RIG012 CAS No.: 2642218-43-5
Purity: 99.53% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameRIG012
DescriptionRIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 μM (measured by NADH-coupled ATPase), and it inhibits the expression of IFN-β and ISG hRsad2.
In vitroRIG012 (1, 1.25, 1.5, 2, 2.5, 3, 4 μM) has potent dose-dependent inhibition of RIG-I signaling in HEK293T cells co-transfected with expression plasmids and reporter plasmids.[1] RIG012 (1.25, 2.25, 4.5, 9, 18 μM) has potent dose-dependent inhibition of IFN-β and ISG hRsad2 expression in A549 cells.[1] RIG012 contains a strong chromophore that absorbs in the visible range (λmax of 470 nm). Upon binding to RIG-I, the 470 nm absorption band of RIG012 undergoes a significant hyperchromic shift toward higher intensity values.[1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 36.43 mg/mL (101.36 mM), Sonication is recommended.
KeywordsRIG-I
Inhibitors RelatedFeeblin | 2',3'-cGAMP sodium | Deucravacitinib | RO8191 | DC-Chol hydrochloride | Icariside I | Interferon receptor inducer-1 | Allura Red AC | Cridanimod | Actarit | CCCP | TNF/IFNγ-IN-1
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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