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Postion:Product Catalog >API>Antineoplastic agents>Other antineoplastic Drugs>Rituximab
Rituximab
  • Rituximab

Rituximab NEW

Price $229 $557 $812
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-06-01

Product Details

Product Name: Rituximab CAS No.: 174722-31-7
Purity: 98.00% Supply Ability: 10g
Release date: 2026/06/01

Product Introduction

Bioactivity

NameRituximab
DescriptionRituximab is an anti-CD20 chimeric monoclonal antibody used to study certain autoimmune diseases and cancers.
Cell ResearchObjective: Complement-mediated cell lysis. Concentrations: 0, 0.02, 0.2, 2, 20 μg/mL. Incubation Time: 2 h. Method: Lymphoma B cells were purified from lymph node biopsies of patients with B-cell lymphoma. Rituximab was added to tumor cells (1×106 /mL) in complete medium supplemented by human serum, inactivated or not by incubation at 56°C for 30 minutes. After 2 hours at 37°C, cell lysis was determined by PI staining of cells and analysis by flow cytometry.
In vitroMETHODS: B cells were treated with 0, 2.5, 5 and 10 μg/mL Rituximab to observe the effect of Rituximab on B cell proliferation. RESULTS There was an optimal inhibition of B cell proliferation at a concentration of 5 μg/mL. [1]
In vivoMETHODS: 100 mg of Rituximab was administered over 4 h. Rituximab was then infused in a regimen of 3 weekly infusions for 4 weeks, and caspase-3 and PARP expression and protein hydrolysis processes were examined in patients. RESULTS Rituximab induced cleavage of caspase-3, followed by the appearance of a 17-kd cleavage product corresponding to the large subunit of the catalytically active protease, and cleavage of PARP, a known substrate of cysteine asparaginase, was also detected. [2]
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsRituximab | FcR
Inhibitors RelatedBenzyl cinnamate | (9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one | Pirazolac | Sodium Iodoacetate | Teneligliptin hydrobromide | Soquelitinib | Difenpiramide | Anti-inflammatory agent 36 | MG-T-19 | Anti-inflammatory agent 35 | Isoegomaketone | Complete Freund's adjuvant

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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