RO-5963 NEW
| Price | $64 | $172 | $239 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-23 |
Product Details
| Product Name: RO-5963 | CAS No.: 1416663-77-8 |
| Purity: 99.36% | Supply Ability: 10g |
| Release date: 2026/04/23 |
Product Introduction
Bioactivity
| Name | RO-5963 |
| Description | RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively). |
| In vitro | RO-5963 (10 μM, 24 hours) potently activates p53 and elevates p21 and MDM2 levels. RO-5963 (10-20 μM; 48 hours) displays much higher apoptotic activity than Nutlin in both MCF7 and ZR75-30 cell lines [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (96.36 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (6.36 mM), Sonication is recommended. |
| Keywords | RO-5963 | RO5963 | RO 5963 | p53-MDMX | p53-MDM2 | p53 | MDMX | Mdm2 |
| Inhibitors Related | 10-Hydroxydecanoic Acid | Flubendazole | Diuron | Gallium maltolate | Rotenone | D-(-)-3-Phosphoglyceric acid disodium | EN219 | Triglycidyl isocyanurate | Indole-3-carbinol | Methyl methanesulfonate | (E/Z)-10-Hydroxy-2-decenoic acid | Magnolol |
| Related Compound Libraries | Ferroptosis Compound Library | Apoptosis Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Inhibitor Library | PPI Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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