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Postion:Product Catalog >RO0270608
RO0270608
  • RO0270608

RO0270608 NEW

Price $117 $289 $479
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: RO0270608 CAS No.: 220846-33-3
Purity: 99.79% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameRO0270608
DescriptionRO0270608, the active metabolite of R411, is an orally active dual α4β1/α4β7 integrin antagonist with anti-inflammatory properties, useful for studying allergic inflammatory responses.
In vitroIn the human T-cell VCAM/anti CD3 costimulation assay, RO0270608 significantly inhibits T-cell proliferation (IC50=30 nM)[2].
In vivoRO0270608, as a dual α4β1-α4β7 integrin antagonist, exhibits favorable pharmacokinetic parameters in vivo[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 8 mg/mL (15.82 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (1.98 mM), Sonication is recommended.
Keywordsα4β7 integrin | α4β1 integrin | RO-0270608 | RO0270608 | RO 0270608
Inhibitors RelatedK34c hydrochloride | Cucurbitacin B | Tirofiban hydrochloride monohydrate | (R)-Leucic acid | Lifitegrast | Cyclo(-RGDfK) | ADH-503 | Elsibucol | CLT-28643 | Bestatin hydrochloride | Gantofiban | 2-hydroxy Flutamide
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Multi-Target Compound Library | Inhibitor Library | Orally Active Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Anhui Ruihan Technology Co., Ltd
2023-08-21

TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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