Manufacturer Provide Pharmaceutical Intermediate Powder Rocuronium Bromide CAS 119302-91-9

Introduction

Product Name: Rocuronium bromide

Other Name :ROCURONIUM BROMIDE;1-[(2b,3a,5a,16b,17b)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide

CAS NO: 119302-91-9

Purity: 99%min
Appearance:White Powder

Molecular formula: C32H53BrN2O4

Molecular weight :609.68

Melting Point :162-164 °C

Rocuronium bromide is a short-acting nondepolarizing steroidal neuromuscular blocker introduced in the U.S.A as Zemuron and in the United Kingdom as Esmeron.     Rocuroniurn bromide has a significantly more rapid onset than other intermediate acting neuromuscular blockers, comparable to succinylcholine but with a very stable cardiovascular profile and has an improved side effect profile.   It has been reported that good to excellent intubation conditions were achieved only one minute after a bolus dose of 600μg/kg of rocuronium bromide.   It has a short duration of action, therefore, is useful for rapid sequence intubation without unacceptable delays in the spontaneous recovery of neuromuscular function.

Application

1. It is a kind of muscle relaxants and a kind of non-depolarizing neuromuscular blocking agents. It is used as the adjuvant drugs for general anesthesia and conventional intubation of both inpatient and outpatient. It can keep the muscle relaxation during the process of mechanical ventilation and surgery.
2. It is used as a kind of skeletal muscle relaxants (non-depolarizing)