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Postion:Product Catalog >Chemical Reagents>Organic reagents>aliphatic ketones>S-(+)-Ketoprofen
S-(+)-Ketoprofen
  • S-(+)-Ketoprofen

S-(+)-Ketoprofen NEW

Price $5 $4 $2
Package 1kg 10kg 100kg
Min. Order: 1kg
Supply Ability: 100kg
Update Time: 2026-07-02

Product Details

Product Name: S-(+)-Ketoprofen CAS No.: 22161-81-5
Min. Order: 1kg Purity: 99%
Supply Ability: 100kg Release date: 2026/07/02
Lead time: in stock Packaging: bag/bottle/drum//IBC, as request
Delivery: By sea, by air, by express Origin: Manufacturer, advantage products
COA, MSDS: Available, contact us for details Contact: Tina

PRODUCT INFORMATION


Names

Namedexketoprofen
SynonymMore Synonyms

 S-(+)-Ketoprofen Biological Activity

DescriptionS-(+)-Ketoprofen is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively.
Related Catalog
Research Areas >> Inflammation/Immunology
Target

COX-1:13 μM (IC50)

COX-2:370 μM (IC50)

In VitroS-(+)-Ketoprofen (Compound 1) is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively[1].
References

[1]. Palomer A, et al. Modeling cyclooxygenase inhibition. Implication of active site hydration on the selectivity ofketoprofen analogues. J Med Chem. 2000 Jun 1;43(11):2280-4.

 Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point431.3±28.0 °C at 760 mmHg
Melting Point75-78oC(lit.)
Molecular FormulaC16H14O3
Molecular Weight254.281
Flash Point228.8±20.5 °C
Exact Mass254.094299
PSA54.37000
LogP2.81
Vapour Pressure0.0±1.1 mmHg at 25°C
Index of Refraction1.592
Storage condition-20°C Freezer

 MSDS

Material Safety Data Sheet

Section1. Identi?cation of the substance
Product Name: (S)-(+)-Ketoprofen
Synonyms:

Section2. Hazards identi?cation
Harmful by inhalation, in contact with skin, and if swallowed.
H301:Toxic if swallowed
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
Very toxic to aquatic life
H400:
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P273:Avoid release to the environment
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:(S)-(+)-Ketoprofen
CAS number:22161-81-5

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
?ushing of the eyes by separating the eyelids with ?ngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire ?ghting measures
In the event of a ?re involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly quali?ed
in the handling and use of potentially hazardous chemicals, who should take into account the ?re,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not speci?ed
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C16H14O3
Molecular weight: 254.3

Section10. Stability and reactivity
Conditions to avoid: Heat, ?ames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN2811Class: 6.1Packing group: III
Proper shipping name: TOXIC SOLIDS, ORGANIC, N.O.S. ((S)-(+)-Ketoprofen)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • CY1572790

  • CHEMICAL NAME :

  • Benzeneacetic acid, 3-benzoyl-alpha-methyl-, (S)-

  • CAS REGISTRY NUMBER :

  • 22161-81-5

  • LAST UPDATED :

  • 199606

  • DATA ITEMS CITED :

  • 1

  • MOLECULAR FORMULA :

  • C16-H14-O3

  • MOLECULAR WEIGHT :

  • 254.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 225 mg/kg/90D-I

  • TOXIC EFFECTS :

  • Gastrointestinal - other changes

  • REFERENCE :

  • TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 30,101,1996

 Safety Information

SymbolArticle illustration Article illustration
GHS06, GHS09
Signal WordDanger
Hazard StatementsH301-H315-H319-H335-H400
Precautionary StatementsP261-P273-P301 + P310-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard CodesXn: Harmful;
Risk PhrasesR25;R36/37/38
Safety Phrases26-60-61
RIDADRUN 2811 6
WGK Germany3
RTECSCY1572790
Hazard Class6.1
HS Code2942000000

 Synthetic Route

Previous 1/12 Next
Article illustration

Ethyl 2-(3-benz...

60658-04-0

~23%

Article illustration

S-(+)-Ketoprofe...

22161-81-5

Literature: Hernaiz, Maria J.; Sanchez-Montero, Jose M.; Sinisterra, Jose V. Tetrahedron, 1994 , vol. 50, # 36 p. 10749 - 10760
Article illustration

Ethyl 2-(3-benz...

60658-04-0

~%

Article illustration

S-(+)-Ketoprofe...

22161-81-5

Article illustration

(2R)-2-(3-Benzo...

56105-81-8

Literature: Journal of Molecular Catalysis B: Enzymatic, , vol. 85-86, p. 23 - 30
Article illustration

ketoprofen

22071-15-4

~94%

Article illustration

S-(+)-Ketoprofe...

22161-81-5

Literature: Camps; Farres; Mauleon; Palomer; Carganico Synthetic Communications, 1993 , vol. 23, # 12 p. 1739 - 1758

 Precursor & DownStream

Precursor  8

Previous 1/2 Next

  • Article illustration CAS#:60658-04-0
    Ethyl 2-(3-benz...

  • Article illustration CAS#:22071-15-4
    ketoprofen

  • Article illustration CAS#:59512-44-6
    3-benzoyl-α-met...

  • Article illustration CAS#:57872-48-7
    methyl α-(m-ben...

DownStream  1


  • Article illustration CAS#:66067-43-4
    3-Ehylbenzophenone

 Customs

HS Code2942000000



Company Profile


Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.



Our Company

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Our Advantage

Rich experience

Our products have been exported to many countries, including Germany, Spain, the United Kingdom, the United States, Australia, the Middle East, Asia, and more. We have received highly positive feedback from our clients and have established long-term friendly cooperative relationships with them.

Excellent quality, purity, and competitive price

Excellent quality is one of the cornerstones of our success. We welcome ordering samples for quality testing.

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Safe and fast delivery

We will arrange shipment of spot products as soon as we receive payment.

Customized products are determined based on the synthesis time of different products.

 

Excellent pre-sales and after-sales service

Pre sales:

We are committed to providing the most favorable quotes and detailed information about our products and company.

after-sale service:

We assist buyers in customs clearance by providing necessary documents and information.

If there is any dispute over product quality, we are committed to providing the best solution.

 

? Packaging: 

1kg/bag, 25kg/drum, 50kg/drum, 180kg/drum, 200kg/drum, 1T/bag/drum, standard export packaging or packaging required by customers


Article illustrationArticle illustration

Shipping

Article illustration

? Delivery:

Within 7 days after receiving your payment


Contact information

For more details, pls contact us freely.

Contact name: Tina

Email address: Tina@fdachem.com

Mob: 86 13213167925

WhatsApp/Skype/Wechat/LINE: 86 15225627621




Company Profile Introduction

Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions. With our agile custom synthesis capabilities and responsive supply chain system, our products have gained widespread adoption across Asian markets including Japan, South Korea, Singapore, and Malaysia, while also expanding deeply into Europe and the Americas. We have forged long-term strategic partnerships with numerous leading global enterprises in the sector. "Driving value through technology and earning trust through service" is our core mission. Looking ahead, we will continue to focus on technological breakthroughs and green innovation in new materials, collaborating with partners to build a high-quality industrial ecosystem and provide globally competitive solutions with greater foresight.

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