S-MTC NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: S-MTC | CAS No.: 156719-41-4 |
| Supply Ability: 10g | Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | S-MTC |
| Description | S-MTC is a selective inhibitor of type I nitric oxide synthase. |
| In vitro | S-MTC (100?μM) is able to obviously reduce nitrite production (25.2±1.1?μM) as compared to Aβ1-42 treatment alone (38.3±2.7?μM) when administered after Aβ1-42 at the 1?h time point. S-MTC (10 or 100?μM) reduces cellular NO release in the absence of Aβ1-42. S-MTC (100?μM) reduces cell viability. Nitrite productions after Aβ1-42 and L-NOARG (100?μM) or Aβ1-42 and S-MTC (100?μM) treatments are significantly lower than Aβ1-42 alone (33.5±2.0 and 34.5±1.6?μM, respectively). S-MTC (100?μM) concentration decreases both MTT (87±1% of control) and NR (80±1% of control, respectively) levels [1]. |
| In vivo | S-MTC is a selective neuronal NOS-inhibitor. The HBO2-induced antinociception is significantly antagonized following pretreatment with S-MTC (i.c.v.). At a dose of 0.3 mg/kg, S-MTC (SMTC) induces a rise in mean blood pressure (BP). At doses of 1.0, 3.0, and 10 mg/kg, S-MTC causes a fall in heart rate, rises in BP, and vasoconstriction in all three vascular beds [2][3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | S-MTC | SMTC | S MTC | NOS |
| Inhibitors Related | 2-Isopropyl-1H-imidazole | Chondroitin sulfate | Aminopicoline | L-Arginine | Agmatine sulfate | 3-AMINO-1,2,4-TRIAZINE | Nitroarginine | Methylene Blue trihydrate | Gluconate Calcium | Diallyl disulfide | Gluconate sodium | Magnesium sulfate |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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