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Postion:Product Catalog >S55746
S55746
  • S55746

S55746 NEW

Price $51 $74 $110
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: S55746 CAS No.: 1448584-12-0
Purity: 99.91% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameS55746
DescriptionS55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).
In vitroS55746 selectively causes apoptosis through BCL-2 inhibition in a BAX/BAK-dependent manner. S55746 (0-1 μM) effectively and selectively induces cell death [1].
In vivoS55746 is a potent and well-tolerated oral BCL-2 inhibitor, effective even at doses up to 300 mg/kg. At doses of 20-100 mg/kg (p.o.), S55746 inhibits xenograft growth in RS4 [1].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 75 mg/mL (105.51 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (2.81 mM), Sonication is recommended.
10% DMSO+90% Saline : 7.5 mg/mL (10.55 mM), Suspension.
KeywordsS-55746 | S55746 | S 55746 | Inhibitor | inhibit | BLC-201 | BLC 201 | Bcl-xL | BCL-201 | BCL201 | Bcl-2 Family | Bcl-2 | BCL 201
Inhibitors RelatedCyanoacetamide | Ascorbyl palmitate | Pendimethalin | Amantadine | Hydralazine hydrochloride | Semaglutide | Estradiol benzoate | Navitoclax | N-Hydroxyphthalimide | Venetoclax | Benzbromarone | Thymoquinone
Related Compound LibrariesHighly Selective Inhibitor Library | Cuproptosis Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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