Sacubitril sodium NEW
| Price | $109 | $147 | $239 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Sacubitril sodium | CAS No.: 149690-05-1 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Sacubitril sodium |
| Description | Sacubitril sodium (AHU-377) is a potent NEP inhibitor with an IC50=5 nM for the treatment of heart failure or in combination with antihypertensive agents. |
| In vivo | In volume-dependent hypertensive rat models, oral administration of Sacubitril sodium (30 and 100 mg/kg) produced a dose-dependent antihypertensive effect in Dahl salt-sensitive (Dahl-SS) rats. In contrast, only modest blood pressure reduction was observed in DOCA-salt rats, despite achieving >95% neprilysin enzyme occupancy at 100 mg/kg, indicating greater sensitivity to neprilysin inhibition in the Dahl-SS model[2]. |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : < 1 mg/mL (insoluble) DMSO : 10 mg/mL (23.07 mM), Sonication is recommended. |
| Inhibitors Related | LHW090-A7 | Sacubitril/Valsartan | Candoxatril | Omapatrilat | Racecadotril | Sacubitril | NEP-IN-1 | Phenylalanylalanine | Sacubitril hemicalcium salt | Thiorphan | Sacubitrilat | Ilepatril TFA |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Bioactive Compounds Library Max |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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