SAFit1 NEW
| Price | $662 | $1090 | $1880 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-21 |
Product Details
| Product Name: SAFit1 | CAS No.: 1643125-32-9 |
| Supply Ability: 10g | Release date: 2026/04/21 |
Product Introduction
Bioactivity
| Name | SAFit1 |
| Description | SAFit1 is a highly potent and selective inhibitor of FK506 binding protein 51 (FKBP51) with a Ki value of 4 ± 0.3 nM, extensively applied in stress biology, neuropsychiatric disorder research, and metabolic disease studies to dissect FKBP51-specific signaling pathways and evaluate its role as a therapeutic target distinct from closely related FKBP family members. |
| In vitro | In neurodevelopmental assays involving N2a, SH-SY5Y neuroblastoma cell lines, and primary hippocampal neurons, SAFit1 acted as a selective FKBP51 inhibitor. It stimulated neurite outgrowth and promoted neuronal differentiation and extension over a concentration range of 1 to 1000 nM [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (106.97 mM), Sonication is recommended. MEthanol : 125 mg/mL (167.14 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 3.3 mg/mL (4.41 mM), Sonication is recommended. |
| Keywords | SAFit-1 | SAFit1 | FKBP52 | FKBP51 |
| Inhibitors Related | Everolimus | Ascomycin | Shield-1 | Tacrolimus monohydrate | ElteN378 | Etonogestrel | GPI-1046 | SAFit2 | GPI-1485 | AP20187 | FKBP12 PROTAC dTAG-13 | Rapamycin |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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