SC 53606 NEW
| Price | $1670 | $2180 | $2800 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-11 |
Product Details
| Product Name: SC 53606 | CAS No.: 151898-33-8 |
| Purity: 99.26% | Supply Ability: 10g |
| Release date: 2026/06/11 |
Product Introduction
Bioactivity
| Name | SC 53606 |
| Description | SC 53606 is a potent and selective 5-HT4 receptor antagonist with a Ki value of 12.3 ± 1.17 nM. SC 53606 antagonizes the vasodilatory effects of 5-HT4 receptor-mediated carbachol-induced contraction. SC 53606 can be used in neuroscience and gastrointestinal pharmacology research. |
| In vitro | Methods: Rat distal colon tissue was placed in an Ussing chamber after the muscular layer was stripped; the tissue was pretreated with 0.2 μM TTX to eliminate neural interference; it was then pretreated with 0.03, 0.1, or 0.3 μM SC 53606 for 20 minutes; 5-HT was added in a stepwise manner at concentrations ranging from 0.1 to 100 μM, and changes in short-circuit current were recorded to plot concentration-response curves. Results: SC 53606 caused a significant concentration-dependent rightward shift in the 5-HT concentration-response curve, significantly increased the EC?? of 5-HT, and competitively inhibited 5-HT-induced Cl? secretion. [3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | SC-53606 | SC 53606 | Debio-1450 | Debio1450 | Debio 1450 | AFN-1720 | AFN1720 | AFN 1720 | Afabicin |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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