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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Indole Compounds>SD-169
SD-169
  • SD-169

SD-169 NEW

Price $34 $51 $75
Package 50mg 100mg 200mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: SD-169 CAS No.: 1670-87-7
Purity: 99.78% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameSD-169
DescriptionSD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
In vivoAnimals were gavaged with Scios SD-169 (10 or 30 mg/kg) or excipient (PEG300) 1 day before and daily after crush injury to the sciatic nerve.?SD-169 is a proprietary oral inhibitor of p38 MAPK activity.?The rate of axonal regeneration was determined by the functional pinch test and was significantly increased in treated animals 8 days after crush injury (P < 0.05;?30 mg/kg dose).?In SD-169-treated animals with nerve transection, nerve fibers regenerating through a silicone chamber were morphologically more mature than untreated nerves when observed 28 days after transection.?TNF immunofluorescence of distal nerve segments after crush injury suggested that SD-169 reduced SC TNF protein[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (6.24 mM), Sonication is recommended.
DMSO : 10 mg/mL (62.43 mM), Sonication is recommended.
Keywordsshock | SD-169 | SD169 | proteins | protein | p38α | p38MAPK | p38 MAPK | p38 | mitogen-activated | MAPK | kinases | Inhibitor | inhibit | HSPs | heat | diabete
Inhibitors RelatedUndecane | Esculin | Bisphenol A | Semaglutide | Fumaric acid | D-Psicose | Skatole | SB 202190 | Afatinib | FERULIC ACID METHYL ESTER | (Rac)-Hesperetin | Nisin Z
Related Compound LibrariesReprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | HIF-1 Signaling Pathway Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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