Se-DMC NEW
| Price | $199 |
| Package | 1mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-25 |
Product Details
| Product Name: Se-DMC | CAS No.: 2098850-81-6 |
| Purity: 98.88% | Supply Ability: 10g |
| Release date: 2026/05/25 |
Product Introduction
Bioactivity
| Name | Se-DMC |
| Description | Se-DMC has antioxidant, anti-damage and anti-edema properties and can be used to study diseases related to metabolism and inflammation. |
| In vivo | METHODS: Se-DMC (5 mg/kg; orally) and meloxicam (5 mg/kg; orally) were both given to mice daily for 14 days, and effects on paw edema, mechanical sensitivity, neurobehavioral deficits (anxiolytic and depressive-like behaviors), Na/K-ATPase activity, oxidative stress, and inflammation were evaluated in CFA-exposed (intramuscular injection 0.1 mL; 10 mg/mL) male Swiss mice were evaluated. RESULTS: Se-DMC decreased paw withdrawal threshold and CFA-induced paw edema. Histopathological results revealed the anti-edema potential of the compound, with a lower number of dilated lymphatic vessels compared to the CFA group. se-DMC reduced the relative mRNA expression levels of tumor necrosis factor-α (TNF-α) and nuclear factor-κB (NF-κB) in the hippocampus and paw of CFA mice. CFA-induced anxiolytic and depressive-like behaviors in elevated plus-maze and tail-suspension tests were reversed to control levels by Se-DMC.Se-DMC decreased paw reactive substance levels and restored superoxide dismutase (hippocampus and paws) and Na/K-ATPase (hippocampus) activities previously increased by CFA. In addition, CFA administration inhibited serum creatinine kinase activity, although the Se-DMC effect did not appear to involve regulation of this enzyme and was equal to or greater than that of meloxicam.Se-DMC attenuated CFA-induced inflammatory responses, injury perception, and neurobehavioral deficits in mice. [1] |
| Storage | Store at low temperature,Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 30 mg/mL (89.91 mM), Sonication is recommended. |
| Keywords | Se-DMC | SeDMC | Se DMC | Antioxidant |
| Inhibitors Related | Thiamine monochloride | Maltol | Butylated hydroxytoluene | AFMK | DL-alpha-Tocopherylacetate | Neohesperidin | Sulbutiamine | L-Cystine | γ-Terpinene | Tyrosol | 4-hydroxyphenylacetic acid | Trolox |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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