Semapimod tetrahydrochloride NEW
| Price | $99 |
| Package | 1mg |
| Supply Ability: | 10g |
| Update Time: | 2025-12-22 |
Product Details
| Product Name: Semapimod tetrahydrochloride | CAS No.: 164301-51-3 |
| Purity: 99.8% | Supply Ability: 10g |
| Release date: 2025/12/22 |
Product Introduction
Bioactivity
| Name | Semapimod tetrahydrochloride |
| Description | Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microglia function. Sematimod tetrahydrochloride inhibits TLR4 signaling, TNF-α, IL-1β, and IL-6, and is used in the study of Crohn's disease and other inflammatory conditions. |
| In vivo | In male OZ rats, Semapimod tetrahydrochloride (5 mg/kg; i.p.; once daily for 2 weeks) restored endothelium-dependent vasorelaxation[1]. |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 1 mg/mL (1.12 mM), Sonication is recommended. H2O : 1 mg/mL (1.12 mM), Sonication is recommended. |
| Keywords | TLR6 | TLR4 | Semapimod | MAPK |
| Inhibitors Related | CMPD1 | Hydroxychloroquine | Chloroquine phosphate | sodium lauroyl-α-hydroxyethyl sulfonate | Chloranil | Chloroquine | CU-115 | NG25 | Imiquimod | TLR3-IN-1 | Resiquimod | Stevioside |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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