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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Seviteronel
Seviteronel
  • Seviteronel

Seviteronel NEW

Price $113 $273 $396
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-21

Product Details

Product Name: Seviteronel CAS No.: 1610537-15-9
Purity: 99.98% Supply Ability: 10g
Release date: 2026/04/21

Product Introduction

Bioactivity

NameSeviteronel
DescriptionSeviteronel (VT-464) is a novel CYP17 cleavage enzyme inhibitor and androgen receptor antagonist used in breast and prostate cancer research.
In vitroSeviteronel (VT-464) selectively inhibits CYP17 17,20-lyase to suppress androgen production without causing mineralocorticoid excess or cortisol depletion[2].
In vivoSeviteronel(100 mg/kg bid; oral administration for 25 days) reduced tumor volume in castrated male mice with xenografts[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 40 mg/mL (100.17 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.01 mM), Sonication is recommended.
KeywordsVT464 | VT 464 | Seviteronel | h-CYP17 Lyase | CYP17 | AndrogenReceptor | Androgen Receptor
Inhibitors RelatedOxadiazon | Musk ketone | Naringin dihydrochalcone | Ipriflavone | Benzyl alcohol | Sudan IV | Enzalutamide | Naringin | Dibenzothiophene | Clarithromycin | Memantine hydrochloride | Flutamide
Related Compound LibrariesFailed Clinical Trials Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Anti-Prostate Cancer Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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