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Postion:Product Catalog >SIC5-6
SIC5-6
  • SIC5-6

SIC5-6 NEW

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Package 1removed
Supply Ability: 10g
Update Time: 2026-05-22

Product Details

Product Name: SIC5-6 CAS No.: 2410846-16-9
Supply Ability: 10g Release date: 2026/05/22

Product Introduction

Bioactivity

NameSIC5-6
DescriptionSIC5-6 is a small-molecule inhibitor of the selective cleavage enzyme (Separase). In HeLa cells, SIC5-6 increases caspase-1 activity in a dose-dependent manner and promotes the cleavage of the Separase substrate Rad21.
In vitroSIC5-6 at concentrations of 30 μM and 100 μM enhances Caspase-1 activity and Rad21 cleavage in HeLa cells. (Rad21: Contains a Separase cleavage site that binds to the fluorescent dye Rh110 ) [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 80 mg/mL (137.58 mM), Sonication is recommended.

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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