Silymarin NEW
| Price | $62 |
| Package | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Silymarin | CAS No.: 65666-07-1 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Silymarin |
| Description | Silymarin is a natural polyphenolic flavonolignan mixture extracted from the seeds of Silybum marianum. It can inhibit tumor cell proliferation and angiogenesis, and improve insulin resistance, thus being widely used in liver disease-related research and adjuvant applications. Studies have shown that silymarin exhibits inhibitory activity against the SARS-CoV-2 main protease, and it has potential research value in the mechanism-related studies of COVID-19. |
| In vitro | Mechanism of Silymarin involves different biochemical reactions, such as stimulation of the rate of ribosomal RNA synthesis by stimulating the transcription of polymerase I and ribosomal RNA genes, blockage of alpha-glycoside loops toxin intake, and protection of cell membranes from free radical-induced damage. Silymarin also displays a substantial protective effect against UVB-induced canceration at different stages, possibly through its strong antioxidant properties. |
| In vivo | The intravenous injection LD50 of Silymarin is 391.4 mg/kg, 70.1 mg/kg, 142.3 mg/kg for mice, rats, rabbits, respectively. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 71.00 mg/mL (147.17 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2.50 mg/mL (5.18 mM), Sonication is recommended. 50% PEG300+50% saline : 20.00 mg/mL (41.46 mM), Suspension. H2O : < 1 mg/mL (insoluble or slightly soluble) Ethanol : 1.00 mg/mL (2.07 mM), Sonication is recommended. |
| Keywords | thistle | Silymarin | Silybin B | SARS-CoV | SARSCoV | SARS coronavirus | resistance | proliferation | Milk | insulin | Inhibitor | inhibit | hepatocellular | HCC | chemopreventive | carcinoma | angiogenesis |
| Inhibitors Related | Nirmatrelvir | EIDD-1931 | Remdesivir | Molnupiravir | Umifenovir hydrochloride | Hydroxychloroquine | Ritonavir | Chloroquine phosphate | Dexamethasone acetate | α-Cyclodextrin | Dexamethasone | Clofoctol |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Failed Clinical Trials Compound Library | Miao medicine Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | NO PAINS Compound Library | Anti-virus Traditional Chinese Medicine Monomer Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Anti-COVID-19 Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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