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Postion:Product Catalog >SJF 8240
SJF 8240
  • SJF 8240

SJF 8240 NEW

Price $1060
Package 5mg
Supply Ability: 10g
Update Time: 2026-07-15

Product Details

Product Name: SJF 8240 CAS No.: 2230821-68-6
Supply Ability: 10g Release date: 2026/07/15

Product Introduction

Bioactivity

NameSJF 8240
Descriptionc-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.
StorageKeep away from direct sunlight,Store under nitrogen, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 55.31 mg/mL (50 mM), Sonication is recommended.
KeywordsSJF-8240 | SJF8240 | SJF 8240
Inhibitors Related(S)-Afatinib | Decanoic Acid | Afatinib Dimaleate | L-Ascorbic acid 2-phosphate trisodium | Bavdegalutamide | Crizotinib | 7-Methoxy-1-tetralone | dBET6 | Tepotinib | Afatinib | Bacitracin Zinc | Vepdegestrant

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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