Product Details
| Product Name:
SJF 8240 |
CAS No.:
2230821-68-6 |
| Supply Ability:
10g |
Release date:
2026/07/15 |
Product Introduction
Bioactivity
| Name | SJF 8240 |
| Description | c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells. |
| Storage | Keep away from direct sunlight,Store under nitrogen,
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 55.31 mg/mL (50 mM), Sonication is recommended.
|
| Keywords | SJF-8240 | SJF8240 | SJF 8240 |
| Inhibitors Related | (S)-Afatinib | Decanoic Acid | Afatinib Dimaleate | L-Ascorbic acid 2-phosphate trisodium | Bavdegalutamide | Crizotinib | 7-Methoxy-1-tetralone | dBET6 | Tepotinib | Afatinib | Bacitracin Zinc | Vepdegestrant |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Suppliers |
Update time |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |