SM-276001 NEW
| Price | $30 | $71 | $107 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-08 |
Product Details
| Product Name: SM-276001 | CAS No.: 473930-22-2 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2026/06/08 |
Product Introduction
Bioactivity
| Name | SM-276001 |
| Description | SM-276001 is a potent, selective agonist of TLR7 and an orally active interferon (IFN) inducer. |
| In vitro | SM-276001 (1 nM-10 μM) activates NF-κB in a dose-dependent manner via human TLR7 [2]. |
| In vivo | Oral administration of 0.1 mg/kg SM-276001 in mice shows potent IFN-inducing activity [1]. Twice weekly oral administration of SM-276001 at a dose of 3 mg/kg significantly reduced disease burden in mice bearing either Renca or CT26 tumors.[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (12.22 mM), Sonication is recommended. DMSO : 100 mg/mL (305.46 mM), Sonication is recommended. |
| Keywords | Toll-like Receptor (TLR) | TLR7 | SM-276001 | SM276001 | SM 276001 | Interferon-α/β receptor | Interferon-alpha/beta receptor | interferon | Inhibitor | inhibit | immune | IFN-α | IFNAR | IFN | antitumor |
| Inhibitors Related | Naproxen sodium | Acetaminophen | Phenidone | Hydroxychloroquine | Benzyl alcohol | Gallic Acid Monohydrate | Diclofenac Potassium | Indomethacin | Paradol | Trometamol | 5-Methylfurfural | Magnesium sulfate |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Cytokine Inhibitor Library | Anti-Alzheimer's Disease Compound Library | Membrane Protein-targeted Compound Library | Orally Active Compound Library | Immuno-Oncology Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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